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A comparative account of microRNA resources, feature-validations and application-based categorizations

ncRNAppi database

Tool namencRNAppi database
URLhttp://ncrnappi.cs.nthu.edu.tw
Important featuresDatabase on pathologically altered microRNA target pathways.
CitationsNg KL, Liu HC, Lee SC. ncRNAppi--a tool for identifying disease-related miRNA and siRNA targeting pathways. Bioinformatics. 2009 Dec 1;25(23):3199-201. Epub 2009 Oct 6. PubMed PMID: 19808883.
Year of publication2009
Rank by usage frequency100
Comments
FunctionFUNCTIONAL ANALYSIS: pathways, DISEASE/ TISSUE SPECIFIC, http://ncrnappi.cs.nthu.edu.tw, Database on pathologically altered microRNA target pathways. , Ng KL- Liu HC- Lee SC. ncRNAppi--a tool for identifying disease-related miRNA and siRNA targeting pathways. Bioinformatics. 2009 Dec 1;25(23):3199-201. Epub 2009 Oct 6. PubMed PMID: 19808883. , 2009, 100, Online/ downloadable , I. QUERY OR INPUT DATA: 1. Select from the given list: miRNA- siRNA or 'Search miRNA or siRNA by Gene (gene name or ID)'. 2. Choose disease assignment for a specific node along miRNA (or siRNA) targeting pathways. To narrow down the number of pathways- select 'Yes' under the 93Express in common pathways94 option. (Abbreviations used: CPW : common pathway- TSG : Tumor suppressor gene- OCG : Oncogene- CRG : Cancer-related gene- R : Receptor- T : Transcription Factor) II. OUTPUT DATA: Table format (results): 1. Targets for input microRNA and their OMIM and KEGG sub-pathway annotations. 2. Targets for input microRNA and their protein-protein interactions- ranking of sub-pathways according to Jaccard index- and their p-values.
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